James Grosfield Professor of Ophthalmology and Visual Sciences
Assistant Professor of Ophthalmology and Visual Science
Ophthalmology and Visual Sciences
1000 Wall Street
Ann Arbor, MI 48105
[email protected]
1000 Wall Street
Ann Arbor, MI 48105
Available to mentor
Jason Miller, MD, PhD
Assistant Professor
Physician-scientist with a clinical practice dedicated to medical retina, and age-related macular degeneration in particular. Bench science lab dedicated to primary and iPSC culture models of age-related macular degeneration.
Miller Lab twitter
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Center MemberCenter for Cell Plasticity and Organ Design
We focus on dry age-related macular degeneration (AMD), and in particular study the lipid biology and metabolism of the primary cell type that dies in this disease, the retinal pigment epithelium (RPE).
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Zhang Q, Shu DY, Bryan RA, Han JYS, Gulette GA, Lo K, Kim LA, Miller JML. J Vis Exp, 2024 Aug 16; (210):Journal ArticleLong-term Monitoring of Oxygen Consumption Rates in Highly Differentiated and Polarized Retinal Pigment Epithelial Cultures.
DOI:10.3791/67038 PMID: 39221933 -
Gulette GA, Hass DT, Pandey K, Zhang Q, Han JYS, Engel A, Chao JR, Philp NJ, Hurley JB, Miller JML. Exp Eye Res, 2024 Aug; 245: 109966Journal ArticleReassessing retinal pigment epithelial ketogenesis: Enzymatic assays for ketone body levels provide inaccurate results.
DOI:10.1016/j.exer.2024.109966 PMID: 38857822 -
Csaky KG, Miller JML, Martin DF, Johnson MW. Am J Ophthalmol, 2024 Jul; 263: 231 - 239.Journal ArticleDrug Approval for the Treatment of Geographic Atrophy: How We Got Here and Where We Need to Go.
DOI:10.1016/j.ajo.2024.02.021 PMID: 38387826 -
Gulette GA, Hass DT, Pandey K, Zhang Q, Han JYS, Engel A, Chao JR, Philp NJ, Hurley JB, Miller JML. bioRxiv,PreprintReassessing Retinal Pigment Epithelial Ketogenesis: Enzymatic Assays for Ketone Body Levels Provide Inaccurate Results
DOI:10.1101/2024.06.03.597221 -
Yousif JE, Miller JML. Ophthalmic Surg Lasers Imaging Retina, 2024 Feb; 55 (2): 100 - 102.Journal ArticleIntraocular Pressure Lowering Associated With Worsening Optic Pit-Like Retinoschisis.
DOI:10.3928/23258160-20231208-01 PMID: 38198609 -
Digsby K, Zhang Q, Miller JML. Eye (Lond), 2024 Jun 13;Journal ArticleBasic science observations link subretinal drusenoid deposit formation to retinal pigment epithelial hypoxia.
DOI:10.1038/s41433-024-03167-1 PMID: 38871936 -
Miller J. 2024PresentationIntroduction to Age-Related Macular Degeneration
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Maiz AM, Murali S, Miller JML. Graefes Arch Clin Exp Ophthalmol, 2024 Jun 7;Journal ArticleRetinal artery occlusion in young patients without typical cardiovascular risk factors: etiologies, prognosis, and suggested work-up.
DOI:10.1007/s00417-024-06527-5 PMID: 38847894
Medicine at Michigan
James Grosfeld has given $11.5 million to Michigan Medicine for research related to dry age-related macular degeneration (AMD).